Female Psychological Disorders Linked To Hormone Levels

Female Psychological Disorders Linked To Hormone Levels

Women are more susceptible to some of the psychological effects linked to stressful experiences at specific stages in their monthly menstrual cycle, scientists from University College London reported in Neurobiology of Learning and Memory.

The authors believe common mental health problems that develop in women might be prevented if specific dates during the menstrual cycle are targeted. They say their study is the first to demonstrate a possible association between psychological vulnerability and a specific moment during the menstrual cycle - which in this case was ovulation.

Repetitive and undesirable thoughts

Repetitive and unwanted thoughts are common symptoms of mood and anxiety disorders. These intrusive thoughts typically occur after a stressful experience; sometimes for a few days, and even weeks or longer.

Dr Sunjeev Kamboj and team set out to determine how vulnerable women are to a stressful event during different stages of their menstrual cycle. The study involved 41 females aged from 18 to 35 years. They all had regular menstrual cycles, and none of them were on the contraceptive pill.

Each participant was asked to watch a 14-minute "stressful" movie which contained death or injury. Saliva samples were taken immediately afterwards so that their hormone levels could be assessed. They were then asked to write down whether they had unwanted thoughts about the video over the next few days, when they had them, and how often.

Intrusive thoughts more common during the early Luteal phase

Sunjeev Kamboj said:

"We found that women in the 'early luteal' phase, which falls roughly 16 to 20 days after the start of their period, had more than three times as many intrusive thoughts as those who watched the video in other phases of their menstrual cycle. This indicates that there is actually a fairly narrow window within the menstrual cycle when women may be particularly vulnerable to experiencing distressing symptoms after a stressful event."

The researchers say that their findings may influence how health care professionals deal with mental health problems in females, especially those who have suffered trauma.

Dr Kamboj said:

"Asking women who have experienced a traumatic event about the time since their last period might help identify those at greatest risk of developing recurring symptoms similar to those seen in psychological disorders such as depression and post-traumatic stress disorder (PTSD).

This work might have identified a useful line of enquiry for doctors, helping them to identify potentially vulnerable women who could be offered preventative therapies.

However, this is only a first step. Although we found large effects in healthy women after they experienced a relatively mild stressful event, we now need to see if the same pattern is found in women who have experienced a real traumatic event. We also need further research to investigate how using the contraceptive pill affects this whole process."

Studies have linked phases of the menstrual cycle to several mental and physical issues, including:

Severity of respiratory symptoms - researchers from Norway reported in the American Journal of Respiratory and Critical Care Medicine that a female's respiratory symptoms may be affected by her menstrual cycle, including asthma symptoms. They tend to get worse during the mid-luteal to mid-follicular phases.

Premenstrual syndrome - symptoms of PMS (premenstrual syndrome) are usually worse for women who feel stressed early on during their menstrual cycle, a team from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the University of Massachusetts-Amherst, and the State University of New York, Buffalo, reported in the Journal of Women's Health.

Knee injuries - researchers from the University of Texas-Austin, and the University of North Carolina-Chapel Hill, suggest that changes across the menstrual cycle in nerves that control muscle activity make female athletes more susceptible to knee injuries, especially anterior cruciate ligament tears and chronic pain. They believe knee injuries are closely linked to the menstrual cycle.

Impulsive spending - as their monthly period approaches, women's spending tends to become more impulsive and less controlled. A team from the University of Hertfordshire, England, reported at the British Psychological Society Annual Conference (April 2009) that hormonal fluctuations may lead to women spending more than they can afford, buying stuff they do not really want, and feeling out of control with money.

Written by Christian Nordqvist
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